Many people take Andipal tablets for blood pressure, not understanding how this effect is expressed, but appreciating its quick and mild hypotensive effect. The drug contains analgesic and antispasmodic components, due to which blood vessels and smooth muscles relax, and the hypotensive effect is secondary. However, doctors successfully use Andipal, prescribing it for the initial stages of hypertension and other concomitant diseases. How the product works, what its composition is, indications and methods of use will be discussed further.
Pharmacodynamics and pharmacokinetics
This is a combined drug that has a vasodilator, analgesic and analgesic effect. A good antispasmodic, which determines the use of Andipal for blood pressure.
Metamizole sodium, which is part of the composition, reduces body temperature and relieves pain. Once in the gastrointestinal tract, the substance is well and quickly absorbed and blocks the prostaglandin system of arachidonic acid, increasing the sensitivity threshold of pain centers in the hypothalamus .
Papaverine hydrochloride dilates blood vessels (reduces the level of calcium in cells) located on the periphery and significantly reduces the overall tone of the smooth muscles of the surface of internal organs.
Bendazole is an antispasmodic, dilates blood vessels, stimulates the spinal cord, and restores nerve endings in the periphery.
Phenobarbital exhibits its sedative properties and enhances the effects of other components of the drug.
Pharmadynamics and pharmacokinetics
Andipal begins to act 15 minutes after administration. This is due to the fact that the active components of the drug are quickly absorbed into the blood. The condition of a person with high blood pressure is normalized by improving cerebral circulation and stopping the release of adrenaline.
Analgin, entering the body, helps reduce the pain symptoms of migraines. The substance also reduces the severity of swelling in soft tissues, which provokes an increase in body temperature.
Papaverine eliminates spasms of smooth muscles in the digestive organs and in the walls of blood vessels. By dilating the arteries, blood flow improves.
Dibazol reduces heart rate and normalizes breathing. Phenobarbital in the drug has a sedative effect on the cells of the central nervous system.
Indications for use of Andipal. What does it help with?
Andipal tablets, what are they for?
- Indications for the use of the drug are migraines of various types.
- Pain associated with spasms of cerebral vessels in the head.
- The medicine helps against pain caused by spasms of smooth muscles or internal organs of the gastrointestinal tract.
- For mild forms of hypertension, it can be used as blood pressure pills.
What blood pressure should I take the medicine for? For primary or secondary hypertension, Andipal can be taken for high blood pressure.
Doctor's recommendations online
When taking Andipal for blood pressure, a rapid therapeutic effect is observed. Its effectiveness is evidenced by reviews from patients suffering from hypertension. Before using the product, you must ensure that there are no contraindications. If you take the medicine for hypotension or to relieve a hangover, you can get negative consequences in the form of nausea, weakness and an allergic reaction. The medication is suitable for one-time or short-term use. For course treatment, Andipal is taken only with the consent of the doctor, since it affects the composition of the blood and is addictive.
Contraindications
- Acute increased sensitivity to the constituent substances of the drug (especially pyrazolone).
- For glucose-6-phosphate dehydrogenase deficiency, various blood diseases, porphyria.
- Severe dysfunction of the kidneys and liver, tachyarrhythmia , angina pectoris, intestinal obstruction .
The use of the drug is contraindicated for children under 8 years of age during lactation.
Side effects
According to the annotation: constipation , nausea , various allergic reactions ( conjunctivitis , urticaria, Quincke's edema ), nephritis , red urine , drowsiness , increased sweating .
With long-term use, agranulocytosis , leukopenia , and thrombocytopenia .
Before use, you should consult your doctor.
Instructions for use of Andipal (Method and dosage)
How to use the drug? Inside. Adults should take 1-2 tablets 2-3 times a day. The full course of treatment should take 7-10 days.
Before taking the medicine, consult your doctor. The course of treatment should be prescribed by a specialist, depending on the nature of the disease and its course. It is not recommended to take the drug for more than 10 days.
How to take if you have high blood pressure? Does Andipal increase or decrease blood pressure?
The drug has a hypotensive effect and is used for high blood pressure. Cannot be used for hypotension, this can lead to harmful changes in the brain.
Reviews
Irina, 34 years old: Andipal helps me with pressure surges - I take one tablet and after 15-20 minutes I feel much lighter. I don’t have chronic hypertension, so I don’t take pills in courses, but only during exacerbations. The doctor recommended that, in addition to medications, I also go on a diet (I’m overweight), I think this will help me quit taking pills completely.
Larisa, 42 years old: I take Andipal in courses because my blood pressure regularly fluctuates. I take 2 tablets a day for 5–7 days, then take a break for 3–4 weeks (as prescribed by the doctor). The product acts gently, reduces blood pressure quickly, I am satisfied with its effect. In addition, Andipal is sold in all pharmacies and is inexpensive.
Elena, 29 years old: I often had a headache, tinnitus, nausea appeared before vomiting. I went to the doctor, and it turned out that I had the initial stage of hypertension, although I had never had any problems with blood pressure before. I was prescribed a general massage, swimming, a salt-free diet and taking Andipal for high blood pressure. The drug is good, it eliminates headaches quickly, it even helps with abdominal pain, I will continue to take it on the doctor’s advice.
Interaction
The use of astringents, enveloping agents and activated carbon reduces absorption in the gastrointestinal tract.
When combined with other antispasmodics and sedatives, the hypotensive effect of the drug is enhanced. diabetes medications increases . Enhances the effect of glucocorticosteroids , Indomethacin and ethanol . Reduces the concentration of cyclosporine in the blood.
Inducers of microsomal liver enzymes ( barbiturate , phenylbutazone ), analeptics ( camphor , Cordiamin ), tonics ( Eleutherococcus , ginseng root) reduce the effectiveness of the drug.
Compatibility of andipal with alcohol
Before using the medicine, you should carefully read the instructions. Andipal absolutely not be taken after alcohol. The drug is also contraindicated in case of hangover.
The recommendations in the instructions cannot be ignored. Alcohol in combination with this drug causes quite serious harm to health. Even a small glass of low-alcohol beer or wine when interacting with the drug leads to severe intoxication.
Andipal is not taken to relieve hangover pain. The body contains a high content of ethanol breakdown products. If you add drug components to them, you get a very dangerous mixture. As a result, toxic and stressful manifestations of the body develop. The negative consequences of combining Andipal with alcohol can even lead to death .
They appear:
- severe nausea and vomiting;
- shortness of breath and lung collapse (compression of one or both lungs, pneumothorax);
- extensive hemorrhages of internal organs;
- dizziness and loss of consciousness;
- exacerbation of stomach and duodenal ulcers;
- coma, even death;
- stroke;
- general deterioration of health associated with severe poisoning;
- some mental reactions (the patient has impaired clarity of thinking, it is difficult for him to navigate in space, he behaves inappropriately).
During treatment with Andipal, it is strictly forbidden to drink alcohol. Tablets can only be taken in a completely sober state.
The medication itself is hepatotoxic. It puts a lot of stress on the liver. In combination with alcohol, this provokes severe pathologies, such diseases as liver failure and cirrhosis are possible. The kidneys are also severely affected.
If the patient has taken Andipal while intoxicated, vomiting must be promptly induced . An adsorbent will help block the effects of toxins. Next you need to call an ambulance.
special instructions
With long-term use of Andipal, the overall picture of peripheral blood should be monitored.
It is recommended to be careful and vigilant when working with mechanisms, due to the fact that the drug significantly affects the change in the reaction rate.
Does the medicine lower or increase blood pressure?
The medicine lowers blood pressure.
At what pressure should Andipal be taken?
With high blood pressure.
Andipal should be used as a medicine for blood pressure after consulting a doctor.
Safe interval
Compatibility between Andipal and alcohol is impossible. The patient must be sober. The drug can be taken no earlier than 12-15 hours after the person drank alcohol. This rule only applies if the dose of alcohol was insignificant.
You should be careful about your health. Taking medications is almost always incompatible with alcohol. And andipal is no exception. In order for the treatment to give positive results, you need to carefully read the instructions for the drug and strictly follow the doctor’s instructions.
Analogues and substitutes
Level 4 ATC code matches:
Analdim
Reopirin
Tempalgin
Spazgan
Benalgin
Pentalgin ICN
Pentalgin N
Pentalgin
Analgin
Renalgan
Tetralgin
Spasmalin
Maxigan
Sedal-M
Piralgin
Baralgin M
Sedalgin Plus
Baralgetas
Revalgin
The drug has no analogues in terms of its main active ingredient.
Analogs for antispasmodic effect:
- Nomigren
- Papazol-UBF
- Papazole
- Urolesan
- No-Shpalgin
- Unispaz
- Teodibaverin
Price for Andipal
Andipal tablets in Russia will cost about 40 rubles per pack of 20 pieces.
In Kyiv pharmacies the price of tablets will be about 20 UAH. for 10 pcs.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Andipal tablets 20 pcs.
PharmstandardOJSC "Pharmstandard-Leksredstva" 39 rub.order - Andipal tab. 10pcs JSC PFK Update
58 RUR order
- Andipal avexima tab. n20 LLC Avexima Siberia
83 RUR order
- Andipal tablets 10 pcs. PharmstandardPharmstandard-Leksredstva OJSC
18 rub. order
- Andipal tablets 20pcs JSC "PFK Obnovlenye"
89 rub. order
Pharmacy Dialogue
- Andipal (tab. No. 20) FS.-Leksredstva
37 RUR order
- Andipal (tab. No. 20)Updating PFC CJSC
90 rub. order
- Andipal (tab. No. 10) FS.-Leksredstva
15 rub. order
- Andipal Avexima tablets No. 20 Anzhero-Sudzhensky chemical-f.z.
83 RUR order
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Pharmacy24
- Andipal forte No. 100 tablets PAT Monfarm, Ukraine
154 UAH.order - Andipal V No. 10 tablets PAT Monpharm, Ukraine
16 UAH order
- Andipal forte No. 10 tablets PAT Monpharm, Ukraine
17 UAH order
- Andipal-V No. 100 tablets PAT Monpharm, Ukraine
152 UAH order
PaniPharmacy
- Andipal tablets Andipal B tablet. No. 10 Ukraine, Monfarm JSC
21 UAH order
- Andipal-Forte tablets Andipal-Forte tablets. No. 100 Ukraine, Monfarm JSC
171 UAH order
- Andipal tablets Andipal-B tablet. No. 100 Ukraine, Monfarm JSC
194 UAH order
- Andipal-Forte tablets Andipal-Forte tablets. No. 10 Ukraine, Monfarm JSC
22 UAH order
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Composition and release form
Andipal is available in the form of round tablets of white or yellowish color. There are distinctive marks on the surface of the tablets. At the pharmacy, the drug is sold in cardboard or paper packages containing 10 tablets of the drug.
1 pill contains the following active ingredients:
- analgin – 0.25g;
- dibazol – 0.02 g;
- papaverine – 0.02 g;
- Phenobarbital – 0.02 g.
Among the auxiliary components of the medication are:
- potato starch – 47.7 mg;
- talc – 9.25 mg;
- stearic acid – 2.9 mg.
