Validol and Corvalol: drug compatibility and main differences

To choose Validol or Corvalol, you need to familiarize yourself with the properties of the drugs. Both drugs have a calming effect. After using drops and tablets, sleep improves, mental state is restored and heart function normalizes. Despite the similarity in composition, the products are different in their effects. The drug should be selected depending on the indications and tolerability of the components.

Both drugs have a calming effect.

Characteristics of Validol

The drug stimulates nerve endings and has a sedative effect. The composition contains a solution of menthol in isovaleric acid menthyl ester. After taking it, blood vessels dilate, blood circulation improves, relaxation is felt, and peptides and histamine begin to be more actively produced. The blood vessels become less permeable, pain is dulled, and nausea disappears.

The treatment is indicated for diseases of the cardiovascular system, which are accompanied by pain. This may be angina pectoris, heart pain due to mental stress, cardialgia.

It is contraindicated to take the medicine if you are allergic to any of the components. pregnancy, breastfeeding, bronchial asthma, in childhood. You can buy sublingual tablets or drops at the pharmacy. The tablets should not be taken if you have diabetes. The action develops within 5-10 minutes. Take 1 tablet 1 time per day. 4-5 drops are dripped onto a piece of sugar. Keep in the mouth under the tongue until completely dissolved.

Validol is contraindicated if you are allergic to the components. pregnancy, breastfeeding, bronchial asthma, in childhood.

Symptoms of drug intoxication

Symptoms of drug poisoning can be very different; the manifestations are mainly determined by the type of drug. A distinctive feature of drug poisoning is its detrimental effect on the central nervous system. Common symptoms include weakness, lethargy, decreased reaction time, or severe psychomotor agitation. Cases of loss of consciousness are known in practice.

One of the common symptoms includes severe headaches. They can even be triggered by hormonal agents, especially if the patient has a predisposition to periodic headaches. When taking hormones, compensatory mechanisms are disrupted, which normally maintain the absence of symptoms. This occurs when taking a large dose of drugs containing caffeine, nitrates, hydralazine, bronchodilators, etc.

An overdose of antibacterial drugs is often accompanied by negative manifestations from the gastrointestinal tract: diarrhea, abdominal pain, increased gas formation. For example, an overdose of penicillin antibiotics leads to rash, vomiting, and convulsions. Excess chloramphenicol can cause heart failure.

Symptoms of poisoning with drugs used to normalize cardiovascular function include:

• heart rhythm disturbance;
• spasms and bradycardia;
• gagging.

An overdose of nonsteroidal anti-inflammatory drugs affects the central nervous system: depression of consciousness, lethargy, lethargy, sleep disturbances, etc. are observed. The use of large amounts of antihistamines (decongestants, antiallergic) drugs can provoke weakness, dilated pupils, hallucinations, and psychomotor agitation.

Poisoning with tranquilizers is dangerous due to disturbances in heart rhythm, suppression of central nervous system function and respiratory disorders, convulsions, severe tremors of the limbs, and hallucinations. The patient's speech may be incoherent and slurred.

It is important to understand that manifestations depend not only on the presence of a particular active substance in the blood, but also on its concentration. Even traditionally beneficial components, such as vitamins, can be harmful and lead to the need for detoxification. What one person can easily endure, another will endure with a whole range of unpleasant manifestations.

Characteristics of Corvalol

The drug belongs to the group of sleeping pills and sedatives, barbiturates. It relieves muscle spasms, calms, and prevents the appearance of exciting currents in the cerebral cortex. It has a tranquilizing and moderate hypnotic effect, relieves vasospasm. The composition contains phenobarbital, mint oil, ethyl ester of a-bromoisovaleric acid. The drug is prescribed for the following diseases and conditions:

• tachycardia;
• increased excitability;
• high blood pressure;
• vascular spasms;
• neuroses;
• vegetative-vascular dystonia;
• insomnia.

You should not start treatment if you are allergic to components, low blood pressure, diabetes mellitus, kidney failure, liver problems, problems with hemoglobin levels, or thyroid diseases. It is forbidden to take by pregnant women and during lactation. Take 15-30 drops with water or 1 tablet twice a day. With long-term use, adverse reactions from the digestive system may appear in the form of nausea, diarrhea, abdominal pain, and flatulence.

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Can Validol and Corvalol be taken together?

The effect of simultaneous administration of validol and corvalol is determined by the dosage. The higher the dose of medications, the higher the risk of developing unwanted reactions. It is important to remember that before taking Corvalol and Validol together, you must consult a specialist.

If validol and corvalol are taken together, the sedative effect increases significantly. In some cases, this condition can lead to coma or syncope. When combined with medications from the nitroglycerin group, cardiovascular collapse may occur.

Difference between drugs

Corvalol has a stronger sedative effect. In addition to the sedative effect, it has an effect similar to a tranquilizer. Corvalol contains phenobarbital. Therefore, the drug is addictive with prolonged use. The drug should also not be taken for drug and alcohol addiction, unlike a similar sedative.

When to take Corvalol and when to take Validol

I take Validol to relieve pain in the heart area. The product helps with motion sickness, neurosis, and hysteria. Corvalol is taken for smooth muscle spasms due to diseases of the intestines and cardiovascular system. It is often used for high blood pressure, neuralgia, mild heart pain, and intestinal spasms.

conclusions

Corvalol differs from Validol in its composition, the presence of bromine and phenobarbital, and ethyl alcohol. This drug is contraindicated in women during pregnancy and lactation, with epilepsy, myasthenia gravis, acute renal or liver failure, respiratory syndrome, drug or drug addiction. In this case, preference should be given to combined herbal preparations, such as Validol or analogues, without barbiturates in the composition. To prevent adverse reactions to the drug, you should consult a physician or cardiologist before taking it.

Reviews from doctors

Elena Romanova, cardiologist

Both drugs dilate the blood vessels of the heart and normalize blood pressure. It is necessary to take in recommended doses to prevent the occurrence of adverse reactions. With prolonged use, medicinal components have a negative effect on the body. For neuroses, Corvalol is prescribed together with Nitroglycerin. If you are having a heart attack, you should not take this medication. In this case, the heart rate will only normalize and the functioning of the nervous system will be restored. You should not increase the dosage if there is no effect within 15-30 minutes.

Evgeniy Sidorenko, therapist

Validol and Corvalol help in relieving the symptoms of neuroses. The composition contains acids that have an antispasmodic effect. These means are one and the same. After taking it, the mental state normalizes, insomnia disappears, headaches and nausea disappear. With each attack of angina, you can drink a few drops to quickly improve the condition. The remedies can complement each other’s action, so you can drink them together. At the same time, the effect of taking it does not increase.

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What is better validol or corvalol

Validol is most often prescribed for mild angina, so patients with this diagnosis should always have such a drug in their medicine cabinet. In addition, the medication is prescribed for psychoses, neuroses and hysterical conditions. Validol helps to cope with insomnia, restore heart rhythm and get rid of feelings of fear. The drug is highly effective for seasickness, when the patient complains of painful headaches. Corvalol is considered an effective sedative, does not provoke allergic reactions and does not accumulate in the body.

If the patient suffers from spasms of the coronary vessels, neuroses and mild hypertension, then experts recommend taking Corvalol. At the same time, such a drug has contraindications for therapy in cases of severe pathologies of the liver and kidneys, as well as during pregnancy.

Side effects

A product such as Validol is easily tolerated. In rare cases, symptoms such as:

• feeling of nausea;
• dizziness;
• tearfulness of the eyes.

Compared to its analogue, Corvalol has more serious side effects. The most dangerous of them is the occurrence of dependence on one of the components of the drug - phenobarbital. And although the amount of this substance in the medicine is insignificant, Corvalol should be used with great caution to prevent the development of psychological dependence.

Existing side effects of the drug also include:

• 
  general weakness;

• speech disorder and coordination problems;
• minor memory disorder;
• disruptions in the functioning of the central nervous system;
• stomach pain;
• development of liver and kidney dysfunction;
• deterioration of concentration.

Due to the possibility of such effects, you should be careful when taking the drug, and if the above symptoms occur, you should stop taking the medicine and go to see a doctor for advice.

Main differences

Both drugs have characteristic differences. The difference between Corvalol and Validol can be determined in the following areas:

1. Compound. The basis of Validol is menthol in the methyl ester of valeric acid. Corvalol, in turn, is a combination drug. It consists of menthol, ethyl ether and phenobarbital. The latter is an antiepileptic drug of the barbiturate group.
2. Different effects on the body. The two drugs have different effects on the body, not only because of their composition, but also because each drug is prescribed for different diseases.
3. Indications for use. Corvalol is used for spasms, and Validol is used for hysterical conditions or migraines.

Indications and contraindications

Both sedatives should not be considered drugs whose actions are aimed at treating specific diseases. They only relieve symptoms of nervous disorders, which can be caused by stress or a nervous breakdown. Therefore, both drugs are symptomatic remedies. However, both medications have both different and similar indications for use (Table 1).

And although both medications are safe, there are contraindications, which include:

• idiosyncrasy of drugs caused by an allergic reaction to one of the constituent components;
• severe diseases or disorders of the liver and kidneys;
• alcoholism;
• epilepsy;
• severe hypotension (a condition characterized by low blood pressure).

Pediatric practice excludes the use of Validol and Corvalol. It is possible to use these medications in children in small dosages, but such treatment must be agreed with a doctor who takes into account the patient’s age, the general picture of the disease and prescribes a dose.