Basophils: essence, norm, causes of deviations

The mobile Internet audience is growing rapidly

66 million Russian users use it along with desktop, and 20 million already access the Internet only from mobile devices - this is 15% more than a year ago.

Pages on smartphones may load slowly

There are several reasons: an unstable network connection, low Internet speed, or the site is not adapted for mobile devices. If you have to wait too long, users will move to other sites.

We offer users Turbo technology

It significantly speeds up the loading of text, images and videos on smartphones and helps save time and megabytes of mobile Internet.

Monetization

Yandex Advertising Network

RTB blocks can display ads from tens of thousands of Yandex advertisers. It is convenient to manage blocks from the partner interface: among them is the popular and profitable Motion.

Direct advertising sales

Manage direct advertiser campaigns through ADFOX or other services.

Business model combinations

Using ADFOX, you can transfer impressions that were not purchased by direct advertisers to YAN, as well as compare the rates of all monetizers in Dynamic monetization.

Development plan

  • Support for multimedia content (illustrations, videos)
  • Support for third party ad networks via ADFOX
  • Support for third-party analytics counters (Google Analytics, Mail.Ru, Rambler Top 100, Mediascope)
  • Speed ​​up loading Turbo pages by 4 times
  • Tables, lists, quotes
  • Image and photo galleries
  • Displaying comments
  • Embed codes for content from YouTube, Vimeo, Instagram, Twitter
  • “Endless” feed (block “You may be interested in”)
  • Site navigation
  • Share button
  • Additional advertising spaces
  • Advanced analytics capabilities
  • Ad rendering speed
  • API for publishing content
  • Call button, chats and feedback forms
  • Support for content embed codes from VKontakte and Odnoklassniki
  • Design customization in CSS
  • Supports GIF animation and video players
  • Editor for debugging Turbo pages
  • Rating block
  • Media content gallery with slider
  • Quickly view a larger image by clicking
  • Content block and anchor links
  • Sidebar – new menu block
  • Additional design types for the “You may be interested in” block
  • Support for embedded content from Yandex.Maps and Yandex.Music
  • Search form - on your website or with sending a request to search engines
  • Impressions of new pages in Turbo format when following links from Turbo pages
  • Product cards for online stores
  • More statistics in Metrica and the ability to use goals
  • Video in Turbo
  • New page types
  • Poll block
  • Advertising optimization - new formats
  • The ability to place a product on Turbo pages in one click so that the user does not leave the accelerated version of the store
  • Custom blocks
  • Authorization
  • Possibility to leave a comment
  • Advanced features of Metrica
  • Feedback from webmasters
  • Expanded appearance customization options

    We have started testing the display of elements created by site owners.
    For example, Turbo pages can have complex interactive components using JavaScript, such as diagrams of the placement of chess pieces or players on the field. But there should be more tools that allow you to flexibly customize Turbo pages - and we, of course, will continue to add them. Please tell us what kind of customization is required for the Turbo pages of your website - leave your contacts in this form, and a specialist from the development team will contact you to clarify the details.

  • New opportunities for online stores

    Online payment and shopping cart will appear in the e-commerce arsenal. Moreover, in the Turbo version of the store you will be able to make purchases directly from the list of products, and after going to the cart, select delivery options. We will add the ability to pre-fill fields (for example, name or contacts) to the order form - if the site visitor is authorized in his Yandex account. It will become more convenient and easier for users to interact with the Turbo version of the store - there will be fewer failures and more conversions.

  • Advanced analytics in Yandex.Metrica

    The Metrics Webvisor tool will help you analyze in detail the behavior of visitors to Turbo pages.
    It records the actions of visitors on the site and shows them in video format - this way you can identify problems in navigation, logic and usability, and as a result, increase site conversion. Metrica will also feature new reports to analyze the effectiveness of the Turbo version of online stores.

  • New blocks and widgets on Turbo pages

    By the end of the year, Turbo pages will have:
    a multi-level menu,

  • customizable dynamic forms,
  • Apester platform embeds for surveys and quizzes,
  • cards for grouping content on a page,
  • possibility of fixing the site header,
  • Scrolling support when viewing an image gallery,
  • “Expand” button to view articles on the desktop,
  • “breadcrumbs” to facilitate navigation on the site,
  • opportunity to comment on articles.

And new widgets - including Market and Zen widgets
- will increase traffic and expand the site’s audience.

  • New advertising formats and optimization opportunities

    • will appear with a parallax effect
      , which will be placed under the site content. The content of such an ad unit appears from underneath the content as the user scrolls the page. The advertisement begins to appear smoothly from the bottom of the banner, and when scrolling, it gradually opens, after which it is just as smoothly and neatly hidden under the content.
    • Fixed horizontal sticky blocks.

  • Advertising in InPage format and the block above the site header will become available for manual placement.
  • Video advertising in InStream (in video content) and InPage (in text content) formats will appear in ADFOX for Turbo pages.
  • Let's provide support design auction

    for Turbo pages. This is a new tool for A/B testing of advertising designs with automatic selection of the most profitable option for each site visitor, which is currently undergoing closed beta testing. It will allow you to choose the optimal design of contextual advertising for a specific site.

  • Let's update the algorithm auto placement of advertisements

    on Turbo pages, we optimize advertising placements and other parameters so that auto placement brings you more income.

  • Reduced basophil levels

    Low levels of basophils are known as basopenia . Basopenia itself is not dangerous to your health, but it can be associated with certain medical conditions. (, , )

    Basophils can penetrate from the blood into areas of inflammation. This migration reduces their circulating amount in the blood . (, )

    When basophils release their granules, they are no longer active. These “empty” cells are not included in the basophil count during the analysis. (, )

    When a low level of basophils is associated with their migration to areas of inflammation, this can serve as an additional argument for doctors when making a diagnosis. ()

    Causes of reduced basophil levels

    Overactive thyroid gland

    Low basophil levels may occur in people with hyperthyroidism or being treated with thyroid hormones. ()

    Hives

    Hives are a type of skin rash with red and raised bumps called blisters. They are very itchy and itchy. This condition is usually caused by an infection or an allergic reaction. ()

    Urticaria is caused by active molecules released by basophils and mast cells . Basophils migrate from the blood into urticaria blisters during disease activity, thereby causing basopenia (a decrease in the number of basophils circulating in the blood). (, , )

    Lupus

    Lupus (systemic lupus erythematosus) is an autoimmune disease in which the immune system attacks healthy tissue. It causes inflammation in various parts of the body (such as joints, skin, heart and brain). ()

    The inflammatory process in lupus causes the accumulation of basophils in secondary lymphatic organs , such as the lymph nodes, tonsils and spleen, which leads to a decrease in the level of basophils in the blood. (, )


    Schematic representation of exacerbation of systemic lupus erythematosus (SLE) by the production of basophil activation-dependent autoantibodies and interleukin IL-17. (source)

    Taking corticosteroids

    Corticosteroids reduce both the activity of basophils and their number. If you take corticosteroids, your basophil levels may be reduced. Talk to your doctor about possible problems you may have while receiving corticosteroids. (, )

    Other diseases

    Anxious depression

    One study of 709 participants linked anxious depression to decreased levels of basophils in the blood. The authors showed a link between inflammation and depression, although no causal conclusions could be drawn. Other multidirectional studies are needed to obtain a more precise relationship. ()

    Smoking

    Smoking activates basophils and decreases the level of intact basophils. Therefore, smoking can theoretically lead to the development of basopenia. However, studies have produced mixed results. One study of 498 people found basophilia (an increase in basophils) in smokers. (, , )

    To improve your appearance

    Support for Turbo pages on a wider class of mobile screens - so that your Turbo pages look equally good not only on mobile, but also on tablets.

    Transferring html layout directly to RSS. To make it more convenient for you to work with the appearance of Turbo pages, we will add the ability to transfer your own html layout directly to RSS. It will be possible to transfer ready-made blocks of your website to the Turbo page practically without changes and not waste time re-configuring the appearance.

    Settings for basic design elements without CSS. And so that you can save time on developing your own CSS, let's add the following features:

    • customize color, font, logo and other elements directly in Webmaster,
    • quickly enable light and dark themes on your website.

    When is it necessary to determine basophils in the blood?

    A blood test to determine the level of basophils is carried out:

    • during routine medical examinations;
    • during examination before hospitalization for surgery;
    • for the purpose of diagnosing infectious diseases, inflammatory phenomena, blood pathologies;
    • to monitor the correctness of treatment.

    The results are interpreted within the limits of the leukocyte formula; blood is not taken separately for basophils in laboratories.

    Based on the level of this type of leukocyte, the doctor receives information about the presence/absence of an inflammatory process, the occurrence of allergic reactions, and may suspect a malignant blood disease. The result must be interpreted by a doctor: hematologist, infectious disease specialist, internist or pediatrician.

    To engage the audience

    Recommendation widget - a block with personalized content for your audience can be added to the Turbo page. This widget is already available to partners of the Advertising Network - it helps to increase the number of transitions to the site and the depth of views.

    Improved automatic recommendation feed. The feed has proven to be an excellent tool for increasing user engagement, and we will continue to improve its effectiveness.

    Working with comments - the ability to monitor the list of articles on which the latest comments appeared, as well as turn comments on and off separately for specific articles.

    Normal indicators

    The blood test form contains two indicators: relative, which shows the proportion of cells in the total number of leukocytes (BA%) and absolute, showing the number of basophils (BA#).

    Each laboratory indicates its own normal ranges on the form, since indicators differ among clinics due to the specific equipment used for laboratory tests.

    The number of basophils does not depend on gender, age, or time of day. Normally, the relative indicator is: 0-1%, absolute: 0-0.09*109/l. The absolute value gives a more complete picture of health. Sometimes it may be necessary to manually determine cell counts under a microscope.

    The interpretation of the tests is carried out by the doctor as a whole, so based on only one indicator it is impossible to establish an accurate diagnosis.

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