Increased intracranial pressure in adults

The drug "No-Shpa" refers to antispasmodic medications. It relieves pain from smooth muscle spasms. The drug is taken to relieve pain in diseases of the stomach, intestines, liver, kidneys and other internal organs. The product rarely causes side effects and is effective.

"No-Shpa": composition and other characteristics

The drug belongs to the category of antispasmodics. Available in the form of tablets (6, 10, 24 pieces in one package) or in the form of injections (25 ampoules of 2 ml each).

The active ingredient is drotavertin (represented as hydrochloride). Each tablet contains 40 mg, each ampoule solution contains 20 mg. In the No-Shpa Forte variety (dosage doubled - 80 mg).

The tablets may have a yellowish, greenish or orange color. The shape of the tablets is round, both surfaces are convex. On one side there is a fault line in the middle, on the other there is a monolithic surface with the inscription “NOSPA”. The solution in the ampoules is also colored in shades of yellow and green.

The shelf life depends on the form of release. Tablets can be stored for 5 years, and ampoules - 3 years from the date of release. The drug is protected from light and stored at room temperature in the range from 15 to 25 degrees.

Attention!

Tablets can be purchased without a doctor's prescription, but injections can only be purchased with a prescription.

Compound

The main active ingredient contained in the drug is drotaverine. This substance is a modified papaverine, a painkiller made from the opium poppy.

1 tablet of No-Shpa contains:

• drotaverine hydrochloride – 40 mg;
• magnesium stearate – 3 mg;
• talc – 4 mg;
• povidone – 6 mg;
• corn starch – 35 mg;
• lactose monohydrate – 52 mg.

The dosage form of the drug is convex yellow tablets with a greenish or orange tint and “spa” engraving on one side.

What do No-Spa tablets help with?

The drug is taken in tablets, as well as in the form of injections (both intramuscularly and intravenously) to quickly relieve spasms of smooth muscles. This is necessary to relieve pain that manifests itself against the background of such diseases:

• pyelitis;
• cystitis;
• cholecystitis;
• papillitis;
• pnephrolithiasis;
• cholecystolithiasis;
• Urolithiasis

“No-Shpu” is also used to relieve spasms associated with pathologies of the stomach and intestines. Such symptoms may occur due to constipation, ulcers, colitis, IBS and other disorders. Another indication for use is headache and dysmenorrhea. However, in this case, the drug will only work if the pain is associated with vasospasm (felt like tension in the head).

In ordinary cases, the “No-Shpa” form is used. An increased concentration in the composition of the drug “No-Shpa Forte” is used if necessary to ensure a lasting long-term effect (for days, weeks in advance). Forte is also taken if it is necessary to reduce the frequency, for example, to 1 time per day.

Effect on pressure

The original drug is produced in Hungary. Release form: capsules or tablets, which are most popular among home consumers, or ampoules with a solution for intramuscular and intravenous injections.

People suffering from blood pressure fluctuations who take the drug often wonder: does nostropin blood pressure increase or decrease, can it be taken to alleviate the condition? These questions are answered below.

Does it lower blood pressure?

High blood pressure (BP) is caused by various factors and has a complex formation mechanism. The drug has no or very little effect on its performance.

Nostropa for high blood pressure is usually used as a remedy for excitatory headaches if they are caused by vasoconstriction.

In this situation, tablets improve blood circulation in the brain.

No-spa for hypertension relieves pressing pain and pulsation around the temples and the back of the head, which is often used for migraine sufferers, especially if it is accompanied by increased blood pressure. But the drug is not indicated as a drug directly for blood pressure.

When taking a drug for hypertension, it is important to make sure there is no overdose, otherwise the readings will drop to a critical level.

Does it increase blood pressure?

No-shpa should be taken with caution if you have low blood pressure. In people with hypotension, vascular tone is impaired, and the drug may worsen their well-being, but will not help normalize blood pressure.

Therefore, there are no indications for taking this drug with low blood pressure to normalize it.

Contraindications for use

Contraindications to the use of the drug are the following diseases and features:

• low cardiac output;
• severe kidney and liver diseases (failure);
• hypersensitivity to the active substance (drotaverine) or to other components in the tablet;
• lactase deficiency (metabolism disorders of galactose and glucose).

During pregnancy (any period), the drug is taken with caution; similar recommendations are for children and people with low blood pressure. It is recommended to consult your doctor first.

During pregnancy

There are no particular contraindications for nasal administration during pregnancy, which runs without complications.

The main activity of the drug is to reduce the contraction, which is not faster, but with a smooth transition to normal. For expectant mothers, it is important that the medicine is not only effective, but also safe for the child. In addition, it works selectively, directly on the muscles of the uterus and other organs.

Often the drug is prescribed before birth to prepare for the normal arrival of the baby and to relieve the mother by optimizing uterine tension.

Despite the safety of the medicine for the expectant mother and child, taking it even for medical reasons (colic, headache) should only occur after consultation with a visiting doctor. The use of NO-SHPA in the first trimester of pregnancy is extremely undesirable as it can reduce the tension of the uterus and cause miscarriage.

If a pregnant woman has low blood pressure, it is recommended to take a horizontal position from the injection to avoid rupees.

Side effects from taking No-Shpa tablets

In most cases, no side effects are observed. But with long-term use, as well as due to the individual characteristics of the body and human condition, the following consequences may appear:

• increased heart rate;
• sleep disorders;
• headaches;
• dizziness;
• decreased blood pressure;
• nausea;
• bowel dysfunction (constipation);
• allergic reactions.

If an injection is administered, a local reaction (redness, foreign sensations) may additionally be observed.

Contraindications

Despite the relative safety of use, and the fact that nasal spray helps relieve spasms, there are some contraindications to its use. The main ones are intolerance to drug components and low blood pressure.

It is also not recommended to take the drug in:

• atherosclerosis;
• Acute failure of the cardiovascular system;
• Glaucoma, high intraocular pressure;
• prostate prostate;
• Severe chronic or acute kidney and liver diseases.

In addition, it is not recommended to take pills to reduce pain in neighbors by the kidneys before the ambulance arrives, because due to their effective work, the clinical picture of the disease can distort the disease, which will interfere with the correct diagnosis. Refusal

No-SHPA is not recommended by many doctors for children under 6 years of age, and is also contraindicated for women while breastfeeding.

Instructions for use "No-Shpa"

Dosage and rules of administration depend on the form of the drug and the age of the person:

1. The daily dosage of the active substance for an adult is in the range of 120-240 mg, which corresponds to 3-6 tablets of the regular drug and 2-3 tablets of the “Forte” variety. In this case, it is allowed to consume no more than 40 mg at a time, i.e. maximum 2 tablets.
2. For children under 11 years of age inclusive, the optimal dose is 80 mg - this amount is taken 2 times a day.
3. For older children, a dose of 160 mg is indicated, divided into 2-4 times.

The general course of therapy (with self-treatment) is no more than 2 days. If during this time your health does not improve, you need to contact a specialist for a possible replacement of the drug and diagnostics. If No-Shpa is used as an additional medication as part of complex therapy, then the course without consulting a specialist can last up to 3 days.

Admission rules

The standing standard for tablets or capsules is 240 mg per day, the maximum single dose is within 80 mg, and the entire volume should be divided evenly over 2-3 times.

When administered intramuscularly, the optimal daily dose is 40-240 mg in 3 injections.

When taking a medicine without consent, it is allowed to use 3 to 6 tablets per day, but not longer than for 2 days. If there is no improvement in your health, go to the clinic to arrange examination and diagnosis.

special instructions

No-Shpa contains lactose, so patients with impaired absorption of glucose and galactose should take the tablets with caution and only after the doctor’s approval.

If the solution is administered intravenously, the patient should lie down for several minutes at rest. If you have high blood pressure, use is allowed only in consultation with your doctor.

The injection solution contains sodium metabisulfite, which can cause an allergic reaction. In rare cases (especially in the presence of bronchial asthma, chronic allergies), bronchospasm and the onset of individual signs of anaphylactic shock are possible.

Features of application

The drug can be used in combination with other drugs, but it is recommended to first consult with your doctor. To get rid of migraines before taking the drug, it is recommended to measure your blood pressure, since this condition is possible with both high and low pressure.

For hypertension

No-aspa as an antispasmodic against the background of high blood pressure is permissible if necessary:

• relieves spasms in the intestines caused by poisoning, uncontrolled medication, but not associated with organ pathology;
• Reducing pain in the lower abdomen and lower back due to cystitis;
• Soothes spasms of the bronchi and lungs during severe coughing.

If the fever is accompanied by cramps, the medicine helps relieve them and is used in combination with antipyretics.

The tablets will have a pronounced antispasmodic effect for spasms of various locations (in the liver, kidneys, intestines) caused by the abuse of alcoholic beverages, spicy and fatty foods. They quickly relieve pain, but do not eliminate the cause of its occurrence.

For hypotension

No-SHPA for low blood pressure is used for the same purposes as for high blood pressure, but must be more careful with respect to the dosage.

If it is exceeded, the drug in people with reduced vascular tension can cause:

• dizziness;
• increased fatigue, drowsiness;
• and poor concentration.

Excessive amounts of the drug cause fainting and confusion.

These side effects most often occur in patients whose blood pressure is below 100/60. This is due to the deterioration of oxygen delivery to the bleeding brain.

Side effects

The body may react adversely to the components of the drug. Possible symptoms include:

• Nervous system: headache, dizziness, sleep disorder, vertigo.
• Cardiovascular system: decreased blood pressure, palpitations.
• Digestive system: nausea, constipation.
• Immune system: allergic reactions (rash, itching, urticaria).

All side effects of the drug are rarely detected: approximately 1 case in 10,000.

An overdose of No-Spa causes cardiac rhythm and conduction problems, which can lead to drug failure and death. In case of an overdose of the drug, you should immediately consult a doctor and subsequently receive symptomatic treatment under his supervision.

Indications and contraindications

You should use No-Shpu with arterial hypotension especially carefully. One tablet of No-Shpa contains 104 mg of lactose, so people with lactose intolerance should limit their intake of No-Shpa to avoid problems with the gastrointestinal tract. Those suffering from galactosemia, lactose deficiency or glucose/galactose malabsorption syndrome should avoid taking this medicine.

Pharmacodynamics

The main component of the drug is drotaverine, which is an isoquinoline derivative. The substance has an antispasmodic effect, reduces the entry of Ca2 into smooth muscle cells, reduces intestinal motility and smooth muscle tone of internal organs, and dilates blood vessels. Does not affect the autonomic nervous system. Unlike papaverine, with which drotaverine is similar in chemical structure and pharmacological properties, it has a strong and long-lasting effect.

Drotaverine has a direct effect on smooth muscles, so it can be used in situations in which drugs from the M-anticholinergic group are contraindicated.

Package

No-Shpa is available in the form of pills and solution for intravenous administration. Tablets of 40 or 80 mg are packaged in plastic blisters of 20 pieces. Each such tablet of medicine, along with instructions, is placed in a cardboard box. The packaging varies depending on the number of tablets inside:

• No. 12: 12 tablets per plate. 1 record per package.
• No. 24: 24 tablets per strip, 1 strip per package.
• No. 60: 60 tablets in a dosing container with protective tape, 1 container per box.
• No. 100: 100 ballet shoes per bottle, 1 bottle per package with a tamper-evident sticker.

The solution for injection is a clear, colorless liquid, which is collected in dark-colored ampoules of 2 ml, which are packed in 5 pieces in a plastic contour package.

Reviews

I was diagnosed with a stomach ulcer quite a long time ago, because of which I often have to suffer from pain in the stomach area. In such cases, I almost always use No-shpa - it is inexpensive and helps quickly - almost always everything goes away in 30 minutes. I did not find any side effects during use. I usually take 2 tablets after meals; if there are any special circumstances, I call my doctor, he will advise me on how to calculate the dosage.

Andrey, 37 years old

Excellent medicine, I have been using it for many years, I always have it on hand. When I take a severe headache along with analgin, they get along well, there are no side effects, and all the symptoms go away. In general, all relatives, when any pain or spasms appear, take noshpa, even my grandmother drinks for high blood pressure.

Irina, 29 years old

I most often take it for headaches, although it also helps with stomach and back pain. A doctor prescribed No-shpa to a friend for prostatitis, and my sister takes it for vegetative-vascular dystonia. It starts to work in about half an hour, not always the effect that we would like, but in terms of price/quality ratio it’s simply top!

Oleg, 26 years old

Question answer

Unlike analgesics, No-shpa eliminates the spasm that causes pain. The medicine has a high safety profile and is well tolerated by various groups of people.

The manufacturer does not indicate the time of taking the drug, so it is most often taken after meals. In order to relieve acute pain, No-shpa can be drunk outside, regardless of meals.

the manufacturer of the original drug has registered the official trademark NO-SHPA, therefore any analogues produced as domestic analogues are fakes. The original packaging of No-shpa contains a holographic image confirming its originality. Another one is to purchase medications from large, reputable chain pharmacies.

Alcohol in large quantities can cause side effects of the drug: headache, dizziness, nausea, heart palpitations, etc. During the course of treatment, you must stop drinking alcohol. It is strictly forbidden to treat hangover syndrome with No-shpa.